Bioconjugated silicon quantum dots from one-step green synthesis.

نویسندگان

  • Romuald Intartaglia
  • Annette Barchanski
  • Komal Bagga
  • Alessandro Genovese
  • Gobind Das
  • Philipp Wagener
  • Enzo Di Fabrizio
  • Alberto Diaspro
  • Fernando Brandi
  • Stephan Barcikowski
چکیده

Biofunctionalized silicon quantum dots were prepared through a one step strategy avoiding the use of chemical precursors. UV-Vis spectroscopy, Raman spectroscopy and HAADF-STEM prove oligonucleotide conjugation to the surface of silicon nanoparticle with an average size of 4 nm. The nanoparticle size results from the size-quenching effect during in situ conjugation. Photoemissive properties, conjugation efficiency and stability of these pure colloids were studied and demonstrate the bio-application potential, e.g. for nucleic acid vector delivery with semiconducting, biocompatible nanoparticles.

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عنوان ژورنال:
  • Nanoscale

دوره 4 4  شماره 

صفحات  -

تاریخ انتشار 2012